Oramed Pharmaceuticals, Inc. |
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Year Ended August 31 |
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Income Statement Data ($K) |
2011 |
2010 |
2009 |
| Total Revenues |
0.0 |
0.0 |
0.0 |
| Operating Loss |
2,435.3 |
2,972.6 |
2,784.1 |
| Financial Income (Expense), net |
14.5 |
10.1 |
21.0 |
| Gain on Sale of Investment |
1,033.0 |
0.0 |
0.0 |
| Pretax Loss (Income) |
1,585.2 |
2,962.4 |
2,763.1 |
| Net Loss (Income) |
1,561.2 |
2,977.4 |
2,760.5 |
| Diluted Loss (Earnings) Per Share ($) |
0.02 |
0.05 |
0.05 |
| Fiscal year ending August 31 |
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| Balance Sheet Data ($K) |
8/31/11 |
8/31/10 |
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Total Cash & ST Investments |
1,513.4 |
1,199.6 |
| Current Assets |
4,284.1 |
1,396.8 |
| Total Assets |
4,325.9 |
1,450.9 |
| Current Liabilities |
441.3 |
458.6 |
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Total Equity |
3,723.9 |
830.3 |
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| Key Financial Ratios |
8/31/11 |
8/31/10 |
| Current Ratio |
9.7x |
3.0x |
| L-T Debt/Equity |
NA |
NA |
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| Dividend Policy |
| Company does not currently pay dividends. |
| Main Shareholders (August 31, 2011) |
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| Nadav Kidron |
15% |
| Zeev Bronfeld |
9% |
| Attara Fund |
9% |
| Hadasit Medical Research Services & Development Ltd. |
6% |
| Leonard Sank |
5% |
| Other private investors |
21% |
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ORMD 0801 - Oral Insulin Capsule Oramed’s Oral Insulin has the potential to create a new paradigm in the treatment of diabetes by allowing insulin to be given at an earlier stage of treatment, and by potentially slowing disease progression. Early intervention is expected to spare beta cells and to improve pancreatic stability. The mechanism of insulin delivery is one that mimics the body’s physiological process, thus decreasing instances of hypoglycemia and other injection-related side effects. The company is now working on an IND submission to the FDA which will be followed by a Phase 2 clinical trial in the US in early 2013. |
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ORMD 0901 - GLP1 Analog Glucagon-like peptide-1 (GLP-1) is an incretin hormone that stimulates the secretion of insulin from the pancreas. In addition, GLP-1 was found to suppress glucagon release from the pancreas, slow gastric emptying to reduce the rate of absorption of nutrients into the bloodstream, and increase satiety. The current market for injectable GLP-1 analog is close to $1 billion and, to-date, they are available only as parenteral dosage forms. With Oramed’s oral delivery of GLP-1 analog, compliance will increase and the side effect of nausea will be reduced. Oramed has conducted pre-clinical and clinical studies with an oral GLP-1 Analog and results showed that it is absorbed from the gastrointestinal tract and can effectively curb glucose excursion post-glucose loading. Further clinical trial are expected in Q3 2012. |
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